Molecular biology of brown adipose tissue.
نویسنده
چکیده
Interest in the biology of brown adipose tissue (BAT) has moved from the field of cold adaptation and cellular bioenergetics to the field of nutrition and obesity in recent years. This is mainly due to studies on BAT of ‘cafeteria-fed’ or obese rodents (Rothwell & Stock, 1979; Himms-Hagen, 1985; Trayhurn, 1986). In fact most studies on BAT have been focused on direct or indirect assay of the uncoupling protein (UCP) of brown adipocyte mitochondria. The main emphasis of the present paper is on the use of molecular biology in BAT. Such an approach has been currently developed for UCP, but could be extended to other components that are essential to BAT activity.
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عنوان ژورنال:
- The Proceedings of the Nutrition Society
دوره 48 2 شماره
صفحات -
تاریخ انتشار 1989